Research
March 2024 - This page is now pending to be updated. The maintenance will be carried out soon.
2022-2023: Surrogate Modelling of Cardiovascular Fluid Dynamics with Physics-Informed Neural Networks
As universal function approximators, deep neural networks have the potential of being the surrogate solver of the Navier-Stokes (NS) equations. This was recently demonstrated via the Physics Informed Neural Network (PINN) on aneurysm flows by Sun et al. However, PINNs are specific to the geometry of the flow domain and require slow training for each new geometric scenario encountered. Here, we present an alternative approach, where a deep learning (DL) side network is cascaded to a PINN domain network for the pre-training of varied geometric cases, which has the potential to enhance network robustness and decrease training complexity.
Presentation - Surrogate Modelling of Fluid Dynamics within Various Vascular Geometries with Physics-Informed Neural Networks.
Check our ESBiomech23 conference abstrct - Pre-Training Varied Vascular Geometries with a Deep Learning Side Network in Physics-Informed Neural Network Simulations of Vascular Fluid Dynamics.
2021-22: Fluid Mechanical Effects of Fetal Aortic Valvuloplasty for Cases of Aortic Stenosis and Evolving Hypoplastic Left Heart Syndrome
Fetal aortic stenosis (AS) with evolving hypoplastic left heart syndrome (feHLHS) causes high risks of progression to HLHS at birth. An in-utero catheter-based intervention, Fetal Aortic Valvuloplasty (FAV), has shown promise as an intervention strategy to circumvent the progression, but its impact on the heart's biomechanics is not well understood. We performed patient-specific computational fluid dynamic (CFD) simulations based on 4D fetal echocardiography to assess the changes in the fluid mechanical environment in the feHLHS left ventricle (LV) before and after FAV.
Check our research article at Annals of Biomedical Engineering - Fluid Mechanical Effects of Fetal Aortic Valvuloplasty for Cases of Aortic Stenosis and Evolving Hypoplastic Left Heart Syndrome.
Past Projects
Archive of my past projects at Imperial College London.